论文部分内容阅读
本文作者应用电镜酶细胞化学方法，对７例进行期团生型与弥生型胃癌患者癌周淋巴结淋巴细胞酶活性进行了研究。结果表明：１．ＡＴＰ酶主要定位于细胞膜胞质面，核膜及染色质等部位也有此酶反应颗粒。Ｇ—６—Ｐ酶主要定位在内质网。ＡＴＰ酶与Ｇ—６—Ｐ酶活性在胃癌组明显减弱，弥生型更为显著。２．５＇－ＮＤ酶定位在内质网、线粒体、核膜等部位。其活性在胃癌组明显增高。结果提示，ＡＴＰ酶与Ｇ－６－Ｐ酶活性下降可能是进行期胃癌患者细胞免疫机能降低的主要原因之一。
The authors used electron microscopy enzymatic cytochemical methods to study the enzymatic activity of lymph node lymphocytes in peripheral lymph nodes in 7 patients with advanced gastric cancer and neoplastic gastric cancer. The results show that: 1. The ATPase is mainly located in the cytoplasmic surface of the cell membrane, and the enzyme membrane is also present in the nuclear membrane and chromatin. The G-6-P enzyme is mainly located in the endoplasmic reticulum. The activities of ATPase and G-6-P enzyme were significantly decreased in gastric cancer group, and the Yayoi type was more significant. The 2.5’-ND enzyme is located in the endoplasmic reticulum, mitochondria, and nuclear membranes. Its activity was significantly higher in the gastric cancer group. The results suggest that the decrease of ATPase and G-6-P enzyme activity may be one of the main reasons for the decrease of cellular immune function in patients with advanced gastric cancer.