冠状动脉粥样硬化性心脏病(冠心病)是导致人类死亡的重要原因。他汀类药物联合阿司匹林肠溶片等抗血小板药物是冠心病患者指南指导下的规范用药方案~([1]),对减轻患者胸闷胸痛症状、减少心肌梗死的发生、改善预后具有非常重要的作用,可降低冠心病的发病率和死亡率~([2-3])。但在临床实践中,尽管依据指南最规范的治疗,冠心病患者仍有胸闷、胸痛等 Coronary atherosclerotic heart disease (coronary heart disease) is an important cause of death in humans. Anti-platelet drugs such as statins and aspirin enteric-coated tablets are standard regimens guided by guidelines of patients with coronary heart disease. [1]) are very important for alleviating the symptoms of chest pain, reducing the incidence of myocardial infarction, and improving the prognosis , Can reduce the incidence of coronary heart disease and mortality ~ ([2-3]). However, in clinical practice, patients with coronary heart disease still have chest tightness, chest pain, etc. despite the most standardized treatment according to the guidelines