急性胰腺炎 (AP)是一种由于各种原因引起胰腺消化酶在胰腺内被激活 ,进而发生胰腺自身消化的化学性炎症 .肝脏是AP时的主要受损器官 ,其损害可加重胰腺炎的病情 ,进而发展成为肝衰竭 ,进一步并发多器官功能障碍综合征 (MODS) ,导致患者高死亡率 .AP时的肝损害机制较复杂 ,就此方面的研究进展作一综述 Acute pancreatitis (AP) is a chemical inflammation that causes pancreatic digestive enzymes to activate within the pancreas due to various causes, thereby causing pancreatic autodigestion. The liver is a major impaired organ at the time of AP, which can aggravate pancreatitis And further develop into liver failure, further complicated by multiple organ dysfunction syndrome (MODS), leading to high mortality in patients.At the time of APA, the mechanism of liver damage is more complicated, and the research progress in this aspect is reviewed