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目的探讨吉林地区2008年6月~2010年12月146例手足口重症病例临床特点进行分析及早期识别进行深入探讨,为今后手足口病早期识别诊治及重症抢救提供理论依据。方法采用回顾性分析对吉林地区2008~2010年手足口病患者相关信息进行分析。结果全部病例中男性居多,发病年龄集中在3岁以下儿童,散居儿童发病高于托幼儿童;吉林地区所辖10个区域均有重症病例发生,主要集中于舒兰市、蛟河市、船营区等地,全年均有发生。重症病例的临床特点是多发生于3岁以下,持续高热、精神差、嗜睡、易惊、肢体抖动、呕吐、白细胞及血糖升高。危重患者可出现脑膜炎、脑炎、脑脊髓炎及肺水肿和循环障碍等;本组患儿采用综合治疗措施的治愈率为100%。结论早期发现、早期治疗及早期识别出重症病例是提高救治水平、降低病死率的关键;
Objective To investigate the clinical features of 146 cases of hand, foot and mouth severe cases in Jilin Province from June 2008 to December 2010 and to make an in-depth study on their clinical features in order to provide a theoretical basis for the early diagnosis and treatment of severe hand-foot-mouth disease. Methods Retrospective analysis of hand-foot-mouth disease in Jilin area from 2008 to 2010 were analyzed. Results The majority of men were found in all the cases, the age of onset was concentrated in children under 3 years of age, and the incidence of diaspora was higher than that of children and kindergarten. In 10 districts under the jurisdiction of Jilin Province, severe cases occurred, mainly in Shulan City, Jiaohe City, Camps and other places, occurred throughout the year. The clinical features of severe cases are more than 3 years of age, sustained high fever, poor spirit, lethargy, easy to panic, limbs jitter, vomiting, white blood cells and elevated blood sugar. Meningitis, encephalitis, encephalomyelitis and pulmonary edema and circulatory disorders may occur in critically ill patients. The overall cure rate in this group of children is 100%. Conclusion Early detection, early treatment and early identification of severe cases are the key to improve the treatment level and reduce the mortality rate.