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喷昔洛韦(penciclovir,PCV)是英国SKB公司开发的开环核苷类抗病毒药物,是前体药物泛昔洛韦(famciclovir,FCV)的代谢产物,有抗单纯疱疹病毒HSV-I,HSV-II,VZV(带状疱疹)和EB病毒的作用,它的作用机制与阿昔洛韦相似,与阿昔洛韦相比,其抗病毒效果显著,是一种抗病毒谱较广的药物[1]?
Penciclovir (PCV) is an open-chain nucleoside antiviral drug developed by SKB Company in UK. It is the metabolite of famciclovir (FCV) and has anti-herpes simplex virus HSV-I, HSV-II , VZV (herpes zoster) and Epstein-Barr virus (EBV). Its mechanism of action is similar to that of acyclovir. Compared with acyclovir, its anti-viral effect is remarkable and it is a drug with a wide range of antiviral spectrum [1 ]?