论文部分内容阅读
众所周知,动脉粥样硬化(动粥)的发病机理与动脉内皮细胞(EC)损伤、血栓形成和脂质浸润关系密切,其中内皮细胞损伤和/或功能紊乱是始动因子,单核一巨噬细胞粘附、血小板功能改变(粘附、聚集、释放增强)和平滑肌细胞(SMC)增殖等为动脉粥样硬化发病的重要环节,从中可知血管壁细胞生物学行为即内皮细胞和平滑肌细胞的功能变化与“动粥”发病的关系更为密切。
It is well-known that the pathogenesis of atherosclerosis (dynamic porridge) is closely related to arterial endothelial (EC) injury, thrombosis, and lipid infiltration. Endothelial cell injury and/or dysfunction are initiating factors, mononuclear-macrophages. Cell adhesion, platelet function changes (adhesion, aggregation, and release enhancement) and smooth muscle cell (SMC) proliferation are important factors in the pathogenesis of atherosclerosis. It is known that the biological behavior of vascular wall cells is the function of endothelial cells and smooth muscle cells. Changes are more closely related to the incidence of “dynamic porridge.”