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目的评估云南省某铅锌矿作业工人尿铅超标者的临床诊断类型,探讨在治疗过程中血铅(PbB)、尿铅(PbU)、红细胞锌原卟啉(ZPP)浓度变化规律,评价驱铅治疗的效果。方法治疗结束后,依据《职业性慢性铅中毒诊断标准》(GBZ 37-2002)进行集体诊断。统计驱铅治疗过程中PbB、PbU、ZPP的值,对数据进行t检验和χ2检验,并对两变量相关性进行直线回归分析。结果 227例尿铅超标者诊断为铅中毒临床观察对象、轻度铅中毒、中度铅中毒的百分率分别为3.07%、2.71%、0.13%;驱铅治疗临床观察对象平均治疗1.92个疗程,轻度铅中毒平均治疗2.76个疗程,中度铅中毒平均治疗3.80个疗程后能达到较为满意的效果。结论该矿企尿铅超标的工人驱铅治疗效果良好。
Objective To evaluate the clinical diagnosis of urinary lead excreted by a lead-zinc mine worker in Yunnan Province, and to explore the changes of PbB, PbU and ZPP in the course of treatment, Lead treatment effect. Methods After treatment, the diagnosis was made according to the diagnostic criteria of occupational chronic lead poisoning (GBZ 37-2002). The values of PbB, PbU and ZPP during the lead-removing treatment were statistically analyzed. The data were analyzed by t-test and χ2 test, and the linear regression analysis of the correlation between the two variables was made. Results 227 cases of urine lead exceeded the clinical observation of lead poisoning, mild lead poisoning, moderate lead poisoning were 3.07%, 2.71%, 0.13%, respectively; lead treatment of clinical observation of the average treatment of 1.92 courses of treatment, light Degree lead poisoning average treatment of 2.76 courses, the average lead poisoning treatment 3.80 courses can achieve more satisfactory results. Conclusion The mine lead excretion of lead exceeded lead workers lead treatment effect is good.