原发性免疫缺陷病的种类颇多,要得到正确的诊断。必需从发病年龄、性别、临床特点及实验室检查结果等诸方面进行综合分析,排除全身性疾病、药物及手术造成的继发性免疫缺陷和患爱滋病的母亲通过垂直感染造成的小儿获得性免疫缺陷病。凡有慢性感染反复发作,间隙期内不完全缓解,治疗反应不佳,或有非寻常致病菌感染者,应高度怀疑免疫缺陷病的存在。如为致病性较低的细菌感染,如白色葡萄球菌败血症等,要考虑嗜中性粒细胞吞噬功能障碍。若特异性免疫功能和吞噬细胞功能正常,尚须研究有无补体缺陷。 There are many types of idiopathic immunodeficiency disease, to get the correct diagnosis. It is necessary to carry out a comprehensive analysis from the aspects of age of onset, gender, clinical features and laboratory test results, to eliminate systemic immunodeficiency caused by diseases, drugs and surgery, and acquired immunity caused by vertical infection by mothers with AIDS Defect disease. Where there is recurrent chronic infection, the gap is not completely relieved during treatment, poor response to treatment, or non-unusual pathogen infection, should be highly suspected of the existence of immunodeficiency disease. Such as low pathogenic bacterial infections, such as Staphylococcus aureus sepsis, etc., to consider neutrophil phagocytic dysfunction. If the specific immune function and phagocyte function is normal, but also have to study whether the complement defect.