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目的: 观察穿透性角膜移植术治疗感染性角膜溃疡的疗效。方法: 采用 M K 液保存的新鲜角膜材料对 26 例 (26 只眼) 严重的细菌、真菌及单疱病毒性角膜溃疡行穿透角膜移植术, 术后随访 12~18 个月。结果: 细菌、真菌及单疱病毒性角膜溃疡的术后植片透明率分别为 7778% 、5385% 、25% , 术后主要的并发症有一过性高眼压、植片排斥及感染复发。结论: 对于药物治疗无效的严重的感染性角膜溃疡, 穿透性角膜移植可有效去除病灶, 重建眼球的完整性, 并为二期光学角膜移植奠定基础。
Objective: To observe the effect of penetrating keratoplasty on infective corneal ulcer. Methods: 26 cases (26 eyes) of severe bacterial, fungal and herpes simplex corneal ulcer were treated with penetrating keratoplasty by fresh corneal material preserved by MK fluid. The patients were followed up for 12-18 months. Results: The postoperative transparence rates of bacterial, fungal and herpes simplex keratoderma were 7778%, 5385%, 25% respectively. The main complications after surgery were transient ocular hypertension, And infection recurrence. Conclusion: Penetrating keratoplasty can effectively remove the lesion and reconstruct the integrity of the eyeball, and lay the foundation for the second stage of optical keratoplasty.