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目的采用治疗药物监测技术为患儿提供合理的抗癫痫个体化治疗方案。方法通过参与癫痫患儿的治疗过程,结合治疗药物监测和高效液相色谱法,分析药物不良反应及药代动力学特点,调整抗癫痫药物的使用。结果与结论患儿病情稳定出院。临床上可结合抗癫痫药物药代动力学特点,在治疗药物监测技术的指导下,提高抗癫痫治疗的有效性和安全性。
Objective To use the drug monitoring technology to provide children with a reasonable individual program of antiepileptic treatment. Methods By taking part in the treatment of children with epilepsy, combined with the treatment of drug monitoring and high performance liquid chromatography, analysis of adverse drug reactions and pharmacokinetic characteristics, adjust the use of antiepileptic drugs. Results and conclusion Children with stable disease were discharged. Clinical pharmacokinetic characteristics of antiepileptic drugs can be combined with the guidance of the therapeutic drug monitoring technology to improve the effectiveness and safety of antiepileptic treatment.