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目的分析蚌埠市第一人民医院急性心肌梗死近20年药物治疗的变化,探讨急性心肌梗死药物治疗进展。方法分别统计该院1989年1月-1999年12月402例(A组)急性心肌梗死和2000年1月-2010年12月414例(B组)急性心肌梗死的常规药物治疗比例和疗效,探讨急性心肌梗死药物治疗进展。结果 A组402例,应用阿司匹林380例,使用率为94.5%,应用肝素或低分子肝素262例,使用率为65.2%,β-受体阻滞剂美托洛尔应用132例,使用率为57.7%,应用他汀类药物240例,使用率为59.7%,B组应用阿司匹林412例,使用率为99.5%,应用肝素或低分子肝素408例,使用率为98.6%,应用β-受体阻滞剂美托洛尔302例,使用率为72.9%,应用他汀类药物396例,使用率为95.7%。B组住院天数减少,院内并发症死亡率降低。结论最近10年阿司匹林、肝素或低分子肝素、β-受体阻滞剂美托洛尔、他汀类药物使用率明显升高,提示该院急性心肌梗死的药物治疗水平也在明显提高。
Objective To analyze the changes of drug therapy in acute myocardial infarction of First People’s Hospital of Bengbu in recent 20 years and to explore the progress of drug treatment in acute myocardial infarction. Methods A total of 402 cases of Acute Myocardial Infarction (A group) and 414 cases of Acute Myocardial Infarction (Group B) from January 2000 to December 2010 were enrolled in this study. To investigate the progress of drug therapy in acute myocardial infarction. Results A group of 402 patients, 380 cases of aspirin, the use rate was 94.5%, the application of heparin or low molecular weight heparin 262 cases, the use rate was 65.2%, metoprolol β-blocker application 132 cases, the use rate was 57.7%. The statins were used in 240 cases, the use rate was 59.7%. In group B, aspirin was used in 412 cases (99.5%), heparin or low molecular weight heparin (408.6% Delayed dose metoprolol 302 cases, the use rate was 72.9%, the application of statins 396 cases, the utilization rate was 95.7%. The number of days in hospitalized in group B decreased and the mortality rate of complications in hospital decreased. Conclusion The use of aspirin, heparin, low molecular weight heparin and metoprolol and statin in the past 10 years has been significantly increased, suggesting that the drug treatment of acute myocardial infarction in this hospital is also significantly improved.