目的研究Mu受体在小鼠树突状细胞中的诱导表达。方法取7～8周龄的C57BL/6J雌鼠骨髓细胞培养,培养7d后,用CD11c+磁珠,采用磁性分选的方法纯化树突状细胞。用免疫荧光染色PCR检测Mu受体及其基因在树突状细胞中的表达。并用流式细胞仪对树突状细胞的表型进行分析。结果Mu受体在激活的树突状细胞上有明显(P<0.05)表达。不同Toll样受体的配体诱导不同程度的Mu受体表达。结论活化的树突状细胞可诱导表达Mu受体。 Objective To study the induction of Mu receptor in mouse dendritic cells. Methods C57BL / 6J female BALB / c mice were cultured in 7-8 weeks old. After cultured for 7 days, dendritic cells were purified by magnetic sorting with CD11c + magnetic beads. Immunofluorescence staining was used to detect the expression of Mu receptor and its gene in dendritic cells. Dendritic cell phenotypes were analyzed by flow cytometry. Results Mu receptor had obvious (P <0.05) expression on activated dendritic cells. Ligands of different Toll-like receptors induce different degrees of Mu receptor expression. Conclusion Activated dendritic cells can induce Mu receptor expression.