我们应用光电镜技术、免疫细胞化学技术和图象分析技术对不同月龄大鼠视上核神经元ＡＶＰ的分泌进行了比较研究。结果：电镜下老龄组神经元胞质内脂褐素较多；ＰＡＰ法显示成龄组ＡＶＰ阳性细胞染色呈深棕色；数据经统计学处理有显著性差异，提示成龄组分泌功能较强而老龄组分泌功能减弱。 We applied light microscopy, immunocytochemistry and image analysis techniques to compare AVP secretion in the supraoptic nucleus neurons of different age groups. Results: There were more lipofuscin in the cytoplasm of the neurons in the aged group under electron microscope. PAP staining showed that the AVP positive cells in the adult group were stained dark brown. The data showed significant difference by statistical analysis, suggesting that the secreting function of the aged group was strong Senescence group secretory function weakened.