本文要点骨质疏松引起的脆性骨折影响着50岁以上1/2的女性及1/5的男性脊椎骨折尤其不易发现和治疗,因此预后差很多药物可有效降低骨折风险患者普遍对骨质疏松治疗的依从性和持续性不佳,可通过对其进行教育来改善少数患者会从二级医疗机构代谢治疗和介入技术的评估中获益,特别是在其他治疗失败的情况下 This article highlights the brittle fracture caused by osteoporosis affecting more than 50 years of age 1/2 of women and 1/5 of male vertebral fractures are not easy to find and treatment, so the poor prognosis of many drugs can effectively reduce the risk of fractures in patients with osteoporosis generally Poor adherence and poor continuity can be improved by educating a minority of patients to benefit from the assessment of metabolic and interventional techniques in secondary care facilities, especially if other treatments fail