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观察２２例脑卒中患者在高压氧治疗不同时期体内自由基代谢物质含量的变化。每天用０．２ＭＰａ高压氧稳压治疗４０ｍｉｎ，连续治疗２０天。结果发现，经高压氧连续治疗１０天，患者血浆ＬＰＯ含量的增加和红细胞ＳＯＤ、ＧＳＨＰｘ活性的下降都不明显（Ｐ＞０．０５），仅红细胞ＧＳＨ含量明显降低（Ｐ＜０．０５）；连续治疗２０天后，患者血浆ＬＰＯ含量明显增高，红细胞ＳＯＤ和ＧＳＨＰｘ活性及ＧＳＨ含量显著下降（Ｐ＜０．０５）。建议可用０．２ＭＰａ高压氧治疗脑卒中患者，每次稳压治疗４０ｍｉｎ，每天治疗１次，连续治疗次数不宜超过２０次。
To observe the changes of free radical metabolites in 22 stroke patients during different periods of hyperbaric oxygen therapy. Every day with 0.2MPa hyperbaric oxygen therapy for 40min, continuous treatment for 20 days. The results showed that the LPO content in plasma and the activity of SOD and GSHPx in erythrocytes were not significantly decreased (P> 0.05), but GSH content in erythrocytes was decreased significantly (P <0.05) after continuous treatment with hyperbaric oxygen for 10 days. After continuous treatment for 20 days, the level of plasma LPO, the activities of SOD and GSHPx and the content of GSH in erythrocytes were significantly decreased (P <0.05). Proposed 0.2MPa hyperbaric oxygen treatment of stroke patients, each regimen 40min, 1 day treatment, the number of consecutive treatment should not exceed 20 times.