婴儿痉挛症是婴幼儿时期全身性癫痫综合征的一种,具有年龄依存性,临床表现为特殊的抽搐形式,脑电图高度失律和智能障碍。多在生后3～7个月发病。此病自1841年West首先发现后,Laidlaw(1976)指出:婴儿痉挛证是在脑发育的特殊阶段中,由许多不同的发病因素引起的特殊抽搐形式。自本世纪五十年代应用激素治疗以来,也出现了不少进展和新的动向,现简述如下。 Infantile spasms are a form of generalized epilepsy syndrome in infancy, age-dependent, clinically manifest as a special form of convulsion, a high level of EEG loss, and mental retardation. More after the onset of 3 to 7 months of life. After the disease was first identified in West in 1841, Laidlaw (1976) pointed out that infantile spasm is a special form of convulsion caused by many different causative factors in a particular phase of brain development. Since the application of hormone therapy in the fifties of this century, a great deal of progress and new trends have also emerged, which are summarized as follows.