临床资料例1患者,女,36岁。主因左小腿黑色肿物2年伴周边红斑反复发作6个月,于2011年10月来我院就诊。2年前患者左小腿无明显诱因出现点状紫红色斑丘疹,渐增大至黄豆大小。因无明显不适感,未予诊疗。近半年来肿物周边出现紫红色瘀斑,反复发作,2周左右可自行消退。长期站立时肿物体积稍增大,瘀斑明显。皮肤科情况:左小腿后侧中部见一1.5cm×1.0 cm的棕黑色结节,边缘不规则,表面光滑,质软,结节周围有一直径约1.5 cm紫红色斑(图1)。皮损组织病理示:表皮基本正常,真皮浅层血管不规则扩张,内皮细胞肿胀,部分呈鞋钉样突向管腔,部分血管周围可见含铁血黄素沉积(图2)。临床表现结合组织病理改变诊断为靶样含铁血黄素沉积性血管瘤。对肿物行完整切除后随访6个月未见复发。例2患者,男,9岁。主因左侧胸部暗红色肿 Clinical data example 1 patients, female, 36 years old. Mainly because of left leg black mass 2 years with peripheral erythema repeated attacks for 6 months, in October 2011 to our hospital. 2 years ago, there was no obvious incentive to the left leg of the spot-like purple rash, increasing to the size of the soybean. Because there is no obvious discomfort, no diagnosis and treatment. Near the past six months there Mucous ecchymosis around the tumor, recurrent, about 2 weeks can be resolved on their own. Long standing tumor volume slightly increased, ecchymosis obvious. Dermatology: A 1.5 cm × 1.0 cm brown-black nodule was seen in the middle of the back of the left leg with an irregular edge. The surface was smooth and soft with a 1.5 cm-diameter purplish red spot around the nodule (Figure 1). Histopathology showed that the epidermis was basically normal, the superficial dermal vessels were irregularly expanded, the endothelial cells were swollen, and some were spike-like to the lumen. Some hemosiderin was seen around the vessels (Fig. 2). Clinical manifestations combined with histopathological diagnosis of the target hemosiderin hemangiomas. No recurrence was observed after 6 months of complete resection of the tumor. Example 2 patients, male, 9 years old. Mainly because of the left chest dark red swollen