PPM1D Silencing by Lentiviral-mediated RNA Interference Inhibits Proliferation and Invasion of Human

来源 :Journal of Huazhong University of Science and Technology(Med | 被引量 : 0次 | 上传用户：candycandy726

【摘要】

：

To construct a lentiviral shRNA vector targeting human protein phosphatase 1D magnesium-dependent(PPM1D) gene and detect its effectiveness of gene silencing in

【作者】

：

王鹏饶竞杨海峰赵洪洋杨林

【机构】

：

DepartmentofNeurosurgery,DepartmentofNeurosurgery

【出处】

：

Journal of Huazhong University of Science and Technology(Med

【发表日期】

：

2011年1期

【关键词】

：

胶质瘤细胞慢病毒载体 SHRNA 干扰抑制细胞增殖人脑侵袭实时定量PCR PPM1D glioma RNA interference lenti

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

To construct a lentiviral shRNA vector targeting human protein phosphatase 1D magnesium-dependent(PPM1D) gene and detect its effectiveness of gene silencing in human gliomas,specific siRNA targets with short hairpin frame were designed and synthesized.DNA

其他文献

Up-regulation of Tim-3 Expression Contributes to Development of Burn-induced T Cell Immune Suppressi

T cell immunoglobulin and mucin domain 3 (Tim-3) is well known to negatively regulate T cells responses, but its role in burn-induced T cells immune suppression

期刊

T细胞亚群免疫抑制TIM烧伤诱导小鼠炎性细胞因子体内T cell immunoglobulin and mucin domain 3T cell

试题库决策支持系统的设计(二)(续)

考试是整个教学过程的重要环节，如何命题出一份高质量的试卷更是十分关键。本文利用决策支持系统的基本原理，设计了试题库决策支持系统（TDSS）。采用该系统后，用户可以在屏幕上任意

期刊

决策支持系统试题库TDSSDSS testing base TDSS

Urolithiasis in Pregnancy： Survey in Clinical Epidemiology

This study examined the association of pregnancy with urolithiasis and provided new insights into urolithiasis in pregnancy. A total of 462 subjects were studie

期刊

怀孕期间尿路结石流行病学调查临床泌尿系结石随机分配替代治疗对照组urolithiasis pregnancy surgical interv

EGFR Inhibitor Enhances Cisplatin Sensitivity of Human Glioma Cells

表皮的生长因素受体(EGFR ) 包括 gliomas 在许多稳固的肿瘤在高水平被发现到快车。这研究是在 glioma 细胞(U87 ) 的生长上与 cisplatin (CDDP ) 独自或在联合检验一个 EGFR

期刊

酪氨酸激酶抑制剂胶质瘤细胞EGFR顺铂表皮生长因子受体敏感性细胞外信号调节激酶神经胶质瘤epidermal growth factor rece

墙体改革·生态环境·居住质量

结合可持续发展思想,简述了墙体改革的必要性、重要性和紧迫性

期刊

墙体改革粘土实心砖生态健康建筑Wallmaterialreform Fired common brick Ecology Healthy buildin

Synthesis and Characterization of UPPE-PLGA-rhBMP2 Scaffolds for Bone Regeneration

A novel unsaturated polyphosphoester(UPPE) was devised in our previous research,which is a kind of promising scaffold for improving bone regeneration.However,th

期刊

poly(lactic-co-glycolicacid)MICROSPHERESBONEmorphogeneticprotein-2UNSATURA

为经济腾飞插上金翅膀

１９９７年以来，平定县根据县里制定的“争创全省一流强县”的目标，以农民文化技术学校为龙头、各专业站室为龙身，围绕粮食、果品、蔬菜、畜牧加工等专业生产技术，着力实施“个、十、百、

期刊

上金培训计划科技骨干高接换优平定县二氧化碳气日光温室养殖工程农村成人教育合理追肥

上海贝岭组建上海岭创微电子有限公司

上海贝岭股份有限公司根据业务发展需要日前组建成立“上海岭创微电子有限公司”，公司注册资本为人民币1000万元，其中：上海贝岭股份有限公司以现金方式出资人民币990万元，占股99％；

期刊

上海贝岭股份有限公司微电子制造海岭业务发展人民币现金股权

Accuracy and Repeatability of Computer Aided Cervical Vertebra Landmarking in Cephalogram

The accuracy and repeatability of computer aided cervical vertebra landmarking (CACVL) were investigated in cephalogram.120 adolescents (60 boys,60 girls) aged

期刊

cervicalVERTEBRALMATURATIONfastMARCHINGmethodparaboliccurvefittingLANDM

Association between SNP rs10569304 on the Second Expressed Region of Hole Gene and the Congenital He

The correlation of single nucleotide polymorphism (SNP) rs10569304 on the second expressed region of hole gene and congenital heart disease (CHD) of human being

期刊

PPM1D Silencing by Lentiviral-mediated RNA Interference Inhibits Proliferation and Invasion of Human

与本文相关的学术论文