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[Objectives] To study the chemical constituents of Pilea sinofasciata C. J. Chen. [Methods] Column chromatography,such as silica gel,Sephadex LH-20 and preparative HPLC were used to isolate and purify the compounds. Spectroscopic methods like MS,1H NMR and~(13)C NMR and physical constants were used to elucidate their structure. [Results]Ninteen compounds were isolated from 95% ethanol extracts of Pilea sinofasciata C. J. Chen,including α-tocopherol(1),stigmasterol(2),epihernandulcin(3),hernandulcin(4),benzoic acid(5),ethyl linolenate(6),ethyl hexadecanoate(7),α-amyrin(8),palmitic acid(9),behenic acid(10),adenosine(11),indole-3-carboxylic acid(12),protocatechuate(13),gallic acid(14),betulinic acid(15),oleanolic acid(16),potassium nitrate(17),diosmetin7-O-β-D-glucopyranoside( 18),3-O-β-D-xylopyranosyl(1→2)-β-D-glucopyranosyl-28-O-β-D-glucopyranosyl oleanolic acid(19). [Conclusions] All of the compounds were isolated from the plant for the first time.
[Objectives] To study the chemical constituents of Pilea sinofasciata CJ Chen. [Methods] Column chromatography, such as silica gel, Sephadex LH-20 and preparative HPLC were used to isolate and purify the compounds. (13) C NMR and physical constants were used to elucidate their structure. [Results] Ninteen compounds were isolated from 95% ethanol extracts of Pilea sinofasciata CJ Chen, including α-tocopherol (1), stigmasterol (2), epihernandulcin (3) , hernandulcin (4), benzoic acid (5), ethyl linolenate (6), ethyl hexadecanoate (7), α-amyrin (8), palmitic acid (9), behenic acid (10) 3-carboxylic acid 12 protocatechuate 13 gallic acid 14 betulinic acid 15 oleanolic acid 16 potassium nitrate 17 diosmetin 7-O-β-D-glucopyranoside 18, 3-O-β-D-xylopyranosyl (1 → 2) -β-D-glucopyranosyl-28-O-β-D-glucopyranosyl oleanolic acid (19). [Conclusions] All of the compounds were isolated from the plant for the first time.