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患者女,42岁.临床诊断:左乳腺癌根治术后.病理:单纯癌,左锁骨上淋巴结、区域淋巴结转移(24/26).软组织转移(+).术后用CMF、CMF+DDP、CAP方案各化疗1周期,疗效维持CR.化疗1个半月后行大剂量化疗和自体骨髓移植.-2d,上午按有核细胞数1.34×10~8/kg共采髓1102ml(毛量);下午行大剂量化疗.预处理方案:CTX 60mg/kg -2d、-1d i.v.d.CBP 800mg/m~2 -2d i.v.d.V_p-16 600mg/m~2 -2d i.v.d.Mesna量为CTX用量的160%,分4次于每次CTX用后0,3,6,9 h给予.+7d,白细胞为零.+8d,血小板达最低值19×10~9/L.感觉头痛.
Female patient, 42 years old. Clinical diagnosis: Left radical mastectomy. Pathology: simple carcinoma, left supraclavicular lymph node, regional lymph node metastasis (24/26). Soft tissue metastasis (+). Postoperative CMF, CMF + DDP, The CAP regimen consisted of one cycle of each chemotherapy regimen, and the efficacy remained as CR. One and a half months after chemotherapy, high-dose chemotherapy and autologous bone marrow transplantation were performed. On the 2nd day, 1102ml (gross) of medulla was harvested in the morning with a nucleated cell count of 1.34×10~8/kg; High-dose chemotherapy in the afternoon. Pretreatment program: CTX 60mg/kg -2d, -1d ivdCBP 800mg/m~2 -2d ivdV_p-16 600mg/m~2 -2d ivdMesna amount is 160% of CTX dosage, minutes 4 times each time after CTX was given 0,3,6,9 h.+7d, leukocytes were 0.+8d, platelets reached the lowest value 19×10~9/L.