论文部分内容阅读
目的探讨雷公藤及其制剂的不良反应与防治措施。方法通过应用雷公藤引起的临床不良反应类型、发生机制及特点、预防措施等方面进行阐述。结果通过改变剂型或改变给药途径及结合现代生物技术,可以降低雷公藤制剂的毒副作用,进而更好地应用于临床治疗。结论严格控制剂量时间,加强监测,开发雷公藤新剂型,减低其毒性,对满足临床用药具有重要意义。
Objective To investigate the adverse reactions and preventive measures of Tripterygium wilfordii and its preparations. Methods through the application of triptolide-induced clinical adverse reactions, the mechanism and characteristics, preventive measures and so on. Results By changing the dosage form or changing the route of administration and combining with modern biotechnology, the toxic side effects of Triptolide can be reduced and thus better applied to clinical treatment. Conclusion Strict control of dose time, strengthen monitoring, the development of new formulations of triptolide, reduce its toxicity, to meet the clinical medication is of great significance.