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报道一例三周大的早产儿(孕33周),应用琥珀胆碱麻醉诱导,呼吸暂停持续20h。术后三天发现患儿是一非典型胆碱酯酶的纯合子(E_(1a),E_(1a))。患儿,3周,2250g。孕33周时经阴道分娩,生后第二天并发败血症,表现为惊厥和频繁的呼吸暂停,头颅超声显示双脑室出血,出血引起的脑积水使侧脑室增大。因脑积水增长拟做Rickham’s贮液器插入,行CSF引流。术前常规化验检查均正常。未用术前药。诱导用Mepleson F系统吸入氟烷,阿托品0.05mg,琥珀胆碱5mg,气管插管。以0.25％氟烷,卡肌宁0.8mg维持。连续监测ECG,BP,SaO_2,ET-CO_2,均在正常范围。手术持续50min,术毕予新斯的明
Reported a three-week-old preterm infants (33 weeks pregnant), induced by succinylcholine anesthesia, apnea lasted 20h. Three days after surgery, the children were found to be homozygous for atypical cholinesterase (E_ (1a), E_ (1a)). Children, 3 weeks, 2250g. 33 weeks pregnant when vaginal delivery, the second day after birth complicated by sepsis, showed convulsions and frequent apnea, head ultrasound showed double ventricular hemorrhage, bleeding caused by hydrocephaly so that the lateral ventricle increases. Due to hydrocephalus growth to be done Rickham’s reservoir insertion, CSF drainage. Preoperative routine laboratory tests were normal. Unused preoperative medicine. Induction with Mepleson F system inhalation of halothane, atropine 0.05mg, succinylcholine 5mg, endotracheal intubation. With 0.25% halothane, card muscle Ning 0.8mg maintenance. Continuous monitoring ECG, BP, SaO_2, ET-CO_2, are in the normal range. Surgery for 50min, surgery to Neostigmine