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目的了解2009-2015年赣州市疑似预防接种异常反应(AEFI)发生特征,评价全市AEFI监测系统运行质量和疫苗接种安全性。方法运用国家AEFI信息管理系统收集个案数据,采用描述性方法进行流行病学分析。结果全市乡报告覆盖率呈逐年上升趋势,7年来共报告AEFI 2 476例,发生率7.15/10万,异常反应发生率1.51/10万剂次。病例以0岁为主,占45.64%;9月报告病例最多,接种后<1天出现反应2 140例,占86.43%;疫苗不良反应发生率居前3位的是百白破、白破和麻风疫苗,临床损害以过敏性皮疹为主。结论全市监测工作取得了非常显著的进步,但监测系统的敏感性有待进一步提高。全市无接种事故,接种服务质量较好。
Objective To understand the characteristics of suspected AEFI in Ganzhou City from 2009 to 2015 and to evaluate the operation quality and vaccination safety of AEFI monitoring system in the city. Methods The national AEFI information management system was used to collect case data and a descriptive method was used for epidemiological analysis. Results The reported coverage of township hospitals showed an upward trend year by year. A total of 476 AEFI cases were reported over the past seven years, with a rate of 7.15 / 100,000 and a rate of 1.51 / 100,000 doses of abnormal reactions. The cases were mainly 0 years old, accounting for 45.64%. The highest reported cases in September were 2 140 cases (86.43%) after 1 day of inoculation. The top 3 cases of vaccine adverse reactions were diterpene, Leprosy vaccine, clinical damage mainly allergic rash. Conclusion The monitoring work in the whole city has made very significant progress, but the sensitivity of the monitoring system needs to be further improved. The city without vaccination accident, vaccination service quality is better.