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目的:探究丙戊酸钠联合卡马西平在治疗额叶癫痫的疗效及安全性。方法:选择额叶癫痫患者92例,分为观察组与对照组,每组46例。对照组给予卡马西平治疗,观察组在此基础上联合丙戊酸钠,观察对比两组临床疗效及药物不良反应。结果:观察组临床总有效率为95.7%,明显高于对照组的80.4%,差异有统计学意义(P<0.05);两组均未发生严重不良反应。结论:丙戊酸钠联合卡马西平治疗额叶癫痫的临床疗效确切,且用药安全,值得临床应用和推广。
Objective: To investigate the efficacy and safety of sodium valproate combined with carbamazepine in the treatment of frontal lobe epilepsy. Methods: 92 patients with frontal lobe epilepsy were selected and divided into observation group and control group with 46 cases in each group. The control group was given carbamazepine treatment. The observation group was combined with sodium valproate on this basis, and the clinical efficacy and adverse drug reactions were compared between the two groups. Results: The total clinical effective rate in the observation group was 95.7%, which was significantly higher than that in the control group (80.4%) (P <0.05). No serious adverse reactions occurred in both groups. Conclusion: The clinical efficacy of sodium valproate combined with carbamazepine in the treatment of frontal lobe epilepsy is accurate, and the medication is safe, it is worth clinical application and promotion.