恶性纤维组织细胞瘤自1964年O′Brien报告以来,文献中对原发于鼻腔鼻窦及喉部者报导甚少。本文综合4篇文稿共7例,其中鼻腔、鼻窦5例:喉部2例,均经病理证实,发病年龄除一例喉部者63岁外,其余均在40岁以下,最小者13岁。全部病例均行手术切除,包括鼻侧切开、上颌骨切除、半喉及全喉切除术,术 Malignant fibrous histiocytoma Since the O’Brien report in 1964, few reports have been reported in the literature on nasal sinuses and throats. In this paper, there are 7 articles in 4 articles, including 5 cases of nasal cavity and paranasal sinuses: 2 cases of larynx were confirmed by pathology. The age of onset except for one case of laryngeal was 63 years old, while the rest were below 40 years old and the smallest was 13 years old. Surgical resection was performed in all cases, including nasal incision, maxillary excision, semi-laryngectomy and total laryngectomy