患者男性,63岁,已婚.因右大腿肌肉、右肩关节及两踝关节肿痛3个月,皮肤大片瘀斑1个月伴便血20天于1988年5月21日入院.既往健康,无出血史,无输血史,家族中无类似出血性疾病.体检:右大腿屈侧肿胀,有压痛,两大腿屈侧及臀部皮肤可见大片瘀斑,直径>5cm,右肩关节活动受限.心肺无异常,肝脾未及,浅表淋巴结不大.实验 Male patient, 63 years old, married because of the right thigh muscle, right shoulder joint and two ankle joint swelling and pain for 3 months, large skin ecchymosis 1 month with blood in the stool 20 days in May 21, 1988. Past health, No history of bleeding, no history of blood transfusion, no bleeding disorder in the family Physical examination: swelling of the right thigh flexion side, tenderness, large thigh ecchymosis on both thigh flexion and buttocks skin, diameter> 5 cm, limited right shoulder movement. No abnormal heart and lung, liver and spleen not, superficial lymph nodes is not large