Work on dynamic topology optimization of engineering structures for vibration suppression has mainly addressed the maximization of eigenfrequencies and gaps between consecutive eigenfrequencies of free vibration, minimization of the dynamic compliance subject to forced vibration, and minimization of the structural frequency response. A dynamic topology optimization method of bi-material plate structures is presented based on power flow analysis. Topology optimization problems formulated directly with the design objective of minimizing the power flow response are dealt with. In comparison to the displacement or velocity response, the power flow response takes not only the amplitude of force and velocity into account, but also the phase relationship of the two vector quantities. The complex expression of power flow response is derived based on time-harmonic external mechanical loading and Rayleigh damping. The mathematical formulation of topology optimization is established based on power flow response and bi-material solid isotropic material with penalization(SIMP) model. Computational optimization procedure is developed by using adjoint design sensitivity analysis and the method of moving asymptotes(MMA). Several numerical examples are presented for bi-material plate structures with different loading frequencies, which verify the feasibility and effectiveness of this method. Additionally, optimum results between topological design of minimum power flow response and minimum dynamic compliance are compared, showing that the present method has strong adaptability for structural dynamic topology optimization problems. The proposed research provides a more accurate and effective approach for dynamic topology optimization of vibrating structures. Work on dynamic topology optimization of engineering structures for vibration suppression has mainly addressed the maximization of eigenfrequencies and gaps between consecutive eigenfrequencies of free vibration, minimization of the dynamic compliance subject to forced vibration, and minimization of the structural frequency response. A dynamic topology optimization method of bi-material plate structures is presented based on power flow analysis. Topology optimization problems directly with the design objective of minimizing the power flow response are dealt with. amplitude of force and velocity into account, but also the phase relationship of the two vector quantities. The complex expression of power flow response is derived based on time-harmonic external mechanical loading and Rayleigh damping. The mathematical formulation of topology optimization is established based on powe rut flow response and bi-material solid isotropic material with penalization (SIMP) model. Computational optimization procedure is developed by using adjoint design sensitivity analysis and the method of moving asymptotes (MMA). Several numerical examples are presented for bi-material plate structures with different, optimum results between topological design of minimum power flow response and minimum dynamic compliance are compared, showing that the present method has strong adaptability for structural dynamic topology optimization problems. The proposed research provides a more accurate and effective approach for dynamic topology optimization of vibrating structures.