病儿,女,9岁。1964年7月9日因怀疑先天性溶血性贫血,脾肿大待查入院。病儿3岁后有咳嗽、盗汗,午后发热。5年前开始反复性发热,有时高达39℃,一年数次。每次持续约7～10天不等。同时发现左上腹部有成人手拳大肿块,质较硬,无痛,逐渐肿大。病后一年腹部膨隆,继之食慾减退,全身乏力,自觉腹部不适,步行困难。近牛年来两下肢浮肿,两小腿及足部有淤血斑点,经常鼻衂血,齿龈出血,但无黄染、血便和呕血 Sick child, female, 9 years old. July 9, 1964 due to suspected congenital hemolytic anemia, splenomegaly pending admission. 3-year-old sick child cough, night sweats, afternoon fever. Repeated 5 years ago began fever, sometimes as high as 39 ℃, several times a year. Each duration of about 7 to 10 days. Also found in the upper left abdomen adult hand fist large mass, hard quality, painless, and gradually enlarged. One year after the illness, the abdomen bulges, followed by loss of appetite, malaise, conscious abdominal discomfort and difficulty walking. Near the past two years, the lower extremity edema, two calves and feet have congestion spots, often nose and throat blood, bleeding gums, but no yellow dye, bloody stool and hematemesis