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血管源性脑水肿 (ｖａｓｏｇｅｎｉｃｃｅｒｅｂｒａｌｅｄｅｍａ ,ＶＣＥ)是指血脑屏障通透性增高造成毛细血管内血浆蛋白与水分渗出 ,引起脑组织水肿。其特征是脑白质水肿明显。本研究从酶屏障的角度观察抗碱性磷酸酶单克隆抗体 (ＡＡＰ)治疗ＶＣＥ ,并与甘露醇进行比较研究
Vasogeniccerebraledema (VCE) refers to the blood-brain barrier permeability increased capillary protein and water exudation, causing brain tissue edema. It is characterized by significant white matter edema. In this study, anti-alkaline phosphatase monoclonal antibody (AAP) was used to treat VCE from the perspective of enzyme barrier and compared with mannitol