患者,女,35岁,咽喉肿痛4d,入院体检:T38.9℃,双侧扁桃体Ⅱ°肿大,无化脓;HR85次·min~(-1),律齐,两肺无干湿哕音,BP120/90mmHg,WBC 15.0×10~9·L~(-1),诊断为上呼吸道感染。该患者无青霉素过敏史,用头孢曲松钠2.0g(哈尔滨制药总厂,批号:20051114)+0.9%氯化钠注射液250 ml静滴,滴速每分钟60滴左右,约30min后病人出现脸色苍白、寒战、呼吸困难、胸闷、烦躁、喉头水肿、四肢冰凉、皮肤瘙痒、口唇发紫、神志不清。立即停止给药,同时吸氧,0.1%肾上腺素0.5ml im,地塞米松10mg+维生素C注射液2g, Patients, female, 35 years old, sore throat 4d, admission examination: T38.9 ℃, bilateral tonsil enlargement Ⅱ, no purulence; HR85 times · min ~ (-1) BP120 / 90mmHg, WBC 15.0 × 10 ~ 9 · L ~ (-1), the diagnosis of upper respiratory tract infection. The patient had no history of penicillin allergy, ceftriaxone 2.0g (Harbin Pharmaceutical Factory, batch number: 20051114) + 0.9% sodium chloride injection of 250 ml intravenous drip rate of 60 drops per minute or so, about 30min after the patient Pale, chills, breathing difficulties, chest tightness, irritability, laryngeal edema, cold limbs, itchy skin, lips purple, unconscious. Immediately stop the administration, while oxygen, 0.1% epinephrine 0.5ml im, dexamethasone 10mg + vitamin C injection 2g,