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目的观察依托咪酯联合米索前列醇阴道给药在无痛人工流产术的临床效果。方法将我院2010年2月至2011年12月期间112例自愿要求无痛人工流产术的早孕妇女随机分为治疗组和对照组。每组56例,术前2h阴道后穹窿放置米索前列醇200ug,治疗组患者依托咪酯静脉麻醉下行人工流产术,对照组患者异丙酚静脉麻醉下手术。结果治疗组给药前后SBP、DBP、HR下降不明显,对照组给药前后下降明显,镇痛有效率治疗组大于对照组。结论依托咪酯联合米索前列醇阴道给药,能有效扩张宫颈,患者血压稳定,镇痛效果确切,效果良好,值得临床推广使用。
Objective To observe the clinical effect of etomidate combined with misoprostol vaginal administration in painless artificial abortion. Methods From February 2010 to December 2011, 112 pregnant women who volunteered to have painless induced abortion were randomly divided into treatment group and control group. Each group of 56 cases, 2 h before vaginal fornix placed misoprostol 200ug, the treatment group patients with etomidate anesthesia down artificial abortion, the control group of patients undergoing propofol anesthesia surgery. Results Before and after treatment, SBP, DBP and HR did not decrease obviously in the treatment group. The control group decreased significantly before and after administration, and the analgesic effective rate in the treatment group was larger than that in the control group. Conclusion The combination of etomidate and misoprostol for vaginal administration can effectively expand the cervix. The patient’s blood pressure is stable, the analgesic effect is accurate and the effect is good, which is worthy of clinical promotion.