地高辛是临床常用的强心药物之一,由于安全范围窄,个体差异大,极易发生中毒反应。本文选七名老年肺心病心衰患者按常规给药方法给予地高辛0.25mg/人。用放免分析方法测定了病人用药后不同时间的血药浓度值。结果七名患者体内药物吸收、分布、代谢及消除都不尽相同。主要表现在药物消 Digoxin is one of the commonly used cardiac drugs in clinic. Due to its narrow safety range and large individual differences, it is extremely apt to cause toxic reactions. In this paper, seven elderly patients with heart failure of pulmonary heart disease given by conventional administration of digoxin 0.25mg / person. The radioimmunoassay method was used to determine the plasma concentration of the patient at different times after treatment. Results Seven patients had different drug absorption, distribution, metabolism and elimination. Mainly in the drug consumption