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N—亚硝基化合物的致癌作用,近十年来有了不少报告。(1)它的前驱物质——各种二级胺和亚硝酸(盐)是日常食品的一部分。(2)用不同结构的N—亚硝基化合物,可以分别使动物的各种脏器致癌(3)如果给于妊娠中的动物N—亚硝基化合物,也可使下一代动物发生癌。
The carcinogenic effects of N-nitroso compounds have been reported for many years. (1) Its precursors - various secondary amines and nitrites - are part of the daily food. (2) Different structures of N-nitroso compounds can cause carcinogenesis of various organs of animals. (3) If given to N-nitroso compounds in animals during pregnancy, cancer of the next generation can also occur.