目前肾性高血压的发病机制,迄今尚未最后阐明,但一般认为由于某些因素引起肾脏缺血,而缺血的肾脏本身可能产生某些加压物质,如肾素(Benin或高血压蛋白原酶)、血管兴奋性物质(VEM)、血压支持素(Pherentasin)等,其中肾素已获得普遍公认。武汉医学杂志《小儿外科副刊》第二卷第二期刊登了《小儿肾性高血压的外科治疗》一文,介绍了本病的发病机制,我们觉得有些问题值得商榷: At present, the pathogenesis of renal hypertension has not yet been finally elucidated, but it is generally considered that renal ischemia is caused by certain factors. The ischemic kidney itself may produce certain pressurized substances such as renin (Benin or Hpv) Enzyme), vascular excitatory substances (VEM), blood pressure support (Pherentasin), etc., of which renin has been generally accepted. Wuhan Medical Journal “Pediatric Surgical Supplement” Volume II, second issue of the “surgical treatment of pediatric renal hypertension,” a article describes the pathogenesis of this disease, we think some questions worth discussing: