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目的:探讨超敏C-反应蛋白(CRP)在西宁地区AECOPD的诊断意义和临床价值。方法:检测50例西宁地区慢性阻塞性肺疾病急性加重期患者和对照组治疗前CRP浓度、并于治疗后复查相关指标。结果:西宁地区慢性阻塞性肺疾病急性加重期患者hs-CRP明显高于对照组,具有统计学意义(P<0.01),治疗后恢复正常,治疗前后比较具有统计学差异(P<0.01)。结论:hs-CRP参与西宁地区慢性阻塞性肺疾病急性加重期炎症过程,是反映AECOPD细菌感染和判断疗效的敏感指标。
Objective: To investigate the diagnostic significance and clinical value of high sensitivity C-reactive protein (CRP) in AECOPD in Xining area. Methods: Fifty patients with acute exacerbation of chronic obstructive pulmonary disease in Xining district were enrolled in the study. CRP concentrations were measured before treatment and after treatment, relevant indexes were examined. Results: The hs-CRP in patients with acute exacerbation of chronic obstructive pulmonary disease in Xining was significantly higher than that of the control group (P <0.01). After treatment, the hs-CRP returned to normal, with statistical significance (P <0.01). Conclusion: hs-CRP is involved in the inflammatory process of acute exacerbation of chronic obstructive pulmonary disease in Xining. It is a sensitive index reflecting AECOPD bacterial infection and judging curative effect.