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目的 研究应用氩离子凝固术(argonplasmacoagulator,APC)治疗隆起糜烂性胃炎的价值及安全性。方法 将 66例隆起糜烂性胃炎患者随机分成A组(先药物后APC治疗组)和B组(药物+APC同时治疗组 ),比较两种方法的疗效。结果 66例患者 51例幽门螺杆菌(Hp)阳性, 36 4% (24 /66)的患者发现肠上皮化生。在A组,单纯药物治疗仅有 15 6% (5 /32 )的患者隆起糜烂性病变消失,而应用APC治疗后, 92 6% (25 /27)的患者隆起糜烂病变消失;在B组,隆起糜烂病变治愈率达 91 2% (31 /34 ),与单纯药物治疗比较差异具极显著性(P<0 01)。APC治疗后仅 1例出现黏膜下气肿,且在 2周后自动吸收。7例出现轻微上腹胀或上腹隐痛,但均在术后 3~7d消失。61例患者共进行了 69次APC治疗,共治疗隆起糜烂性病变 352个,平均每次治疗用时为 11min。结论 隆起糜烂性胃炎的发病与Hp感染有关,容易发生肠上皮化生。单纯药物治疗疗效欠佳。APC治疗隆起糜烂性胃炎不仅疗效显著,而且安全简便。
Objective To study the value and safety of argon plasma coagulation (APC) in the treatment of erosive gastritis. Methods Sixty-six patients with erosive gastritis were randomly divided into group A (the first drug-treated APC group) and group B (drug + APC group). The curative effect of the two methods were compared. Results Totally 51 patients with Helicobacter pylori (Hp) were positive in 66 patients and intestinal metaplasia was found in 36 4% (24 of 66 patients). In Group A, the erosive lesions disappeared in 15 6% (5/32) of the patients treated with simple drug therapy, while the lesions of the erosive erosions disappeared in 92 6% (25 of 27) patients treated with APC. In Group B, The cure rate of bulging erosive lesions was 91 2% (31/34), which was significantly different from that of drug treatment alone (P <0.01). Only 1 patient developed submucosal emphysema after APC treatment and absorbed automatically after 2 weeks. 7 cases of slight abdominal distension or upper abdominal pain, but all disappear after 3 ~ 7d. A total of 61 patients underwent APC treatment 69 times, a total of 352 patients with erosive erosive lesions, with an average of 11min for each treatment time. Conclusion The incidence of erosive gastritis is associated with Hp infection, prone to intestinal metaplasia. Simple drug treatment ineffective. APC treatment of erosive erosive gastritis not only significant effect, but also safe and easy.