复方硫酸沙丁胺醇联用布地奈德治疗哮喘的疗效观察

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目的探讨复方硫酸沙丁胺醇气雾剂联用布地奈德气雾剂治疗支气管哮喘的临床疗效。方法回顾性分析我科收治的84例支气管哮喘患者的临床资料,给予分析和统计。随机将84例患者分为观察组和对照组各42例,观察组采用复方硫酸沙丁胺醇气雾剂,每揿含硫酸沙丁胺醇120μg,异丙托溴铵20μg,共2揿,4次/d吸入;对照组采用吸入皮质激素布地奈德200μg,联合复方沙丁胺醇气雾剂,每揿含硫酸沙丁胺醇120μg,3次/d吸入。结果观察组10 d内症状明显缓解率95.23%,平均症状明显缓解时间为3 d,平均为2 d,对照组10 d内症状明显缓解率73.8%,平均症状明显缓解时间为8 d,平均为5 d;观察组疗效显著优于对照组(P<0.01),观察组用药后肺功能改善情况也明显优于对照组(P<0.05)。结论复方硫酸沙丁胺醇气雾剂联用布地奈德治疗支气管哮喘疗效肯定,患者易于接受,值得临床推广。 Objective To investigate the clinical efficacy of compound salbutamol sulfate aerosol combined with budesonide aerosol in the treatment of bronchial asthma. Methods The clinical data of 84 patients with bronchial asthma admitted to our department were retrospectively analyzed and analyzed. 84 patients were randomly divided into observation group and control group, 42 cases in the observation group using compound salbutamol sulfate aerosol, each containing 120μg salbutamol sulfate, ipratropium bromide 20μg, a total of 2 揿, 4 times / d inhalation; Control group inhaled corticosteroid budesonide 200μg, combined with compound salbutamol aerosol, each containing salbutamol sulfate 120μg, 3 times / d inhalation. Results In the observation group, the symptom relief rate was 95.23% in 10 days, and the mean symptom relief time was 3 days (average 2 days). In the control group, the symptom relief rate in 10 days was 73.8% and the average symptom relief time was 8 days The effect of observation group was significantly better than that of control group (P <0.01). The improvement of pulmonary function in observation group was also better than that of control group (P <0.05). Conclusions The compound salbutamol sulfate aerosol combined with budesonide is effective in treating bronchial asthma. The patients are easy to accept and worthy of clinical promotion.
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