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为了证实一侧后牙缺失导致颞下颌关节各部份负荷发生变化，从而引起相应的组织学变化。本研究在１２头小型猪拔除一侧上下尖牙及后牙并分别于１和３个月后处死动物取标本，以６头小型猪作为对照。结果发现，所有实验组动物的颞下颌关节组织均出现明显退行性改变，拔牙侧髁突可见玻璃样血栓形成，提示局部微循环障碍，一侧牙缺失可影响两侧颞下颌关节，失牙侧受累较非失牙侧明显，且随时间发展而加重。
In order to confirm that one side of the posterior teeth missing lead to changes in the various parts of the temporomandibular joint load, which caused the corresponding histological changes. In this study, 12 miniature pigs were removed from one side of the upper and lower canines and posterior teeth and were sacrificed 1 and 3 months after the animals were taken specimens to 6 miniature pigs as a control. The results showed that all the experimental animals in the temporomandibular joint tissues were significantly degenerative changes in the extraction side of the condyles can be seen glass thrombosis, suggesting that local microcirculation, loss of one side of the teeth can affect both sides of the temporomandibular joint, loss of teeth side Involved more than non-loss side obvious, and with the development of time and aggravate.