论文部分内容阅读
目的 :为少儿感染性心内膜炎 (IE)的诊治及预防寻找对策。方法 :对 2 0例少儿 IE的临床资料进行回顾性分析。结果 :IE2 0例中 ,非青紫型先天性心脏病 1 0例 ,均为室间隔缺损 (VSD) ,其中 5例合并主动脉瓣关闭不全 (AI) ;青紫型先天性心脏病 2例 ;风湿性心脏病 6例 ;心脏结构正常 2例。部分患者伴有明显的免疫功能紊乱。血培养阳性 1 0例。超声心动图检查发现瓣膜赘生物1 7例。治疗主要用青霉素等。死亡 5例。结论 :1心脏结构异常是 IE的主要基础病因 ;2先天性心脏病 VSD合并 AI、风湿性心脏病有二尖瓣脱垂和联合病变者为发生 IE的高危儿 ,对这些患儿应定期用抗生素积极预防 ;3超声心动图检查对 IE的诊断有重要价值。4对确诊或高度疑诊的 IE患儿 ,首先应内科治疗。
Objective: To find out the countermeasures for diagnosis and treatment of children with infective endocarditis (IE). Methods: The clinical data of 20 children with IE were analyzed retrospectively. Results: Among 10 cases of IE2, 10 cases of non-purple type congenital heart disease were all ventricular septal defect (VSD), of which 5 cases were complicated with aortic valve insufficiency (AI), 2 cases of cyanotic congenital heart disease, 2 cases of rheumatoid 6 cases of heart disease; 2 cases of normal heart structure. Some patients with significant immune dysfunction. Blood culture positive 10 cases. Echocardiography revealed valvular vegetation in 17 cases. Main treatment with penicillin and so on. 5 died. Conclusion: 1 heart structural abnormalities is the main underlying cause of IE; 2 congenital heart disease VSD with AI, rheumatic heart disease with mitral valve prolapse and joint disease for the occurrence of high-risk children with IE, these children should be regularly used Antibiotics, active prevention; 3 echocardiography has important value in the diagnosis of IE. 4 pairs of diagnosed or highly suspected children with IE, the first medical treatment should be.