某些慢性充血性心力衰竭患者症状持续,常规疗法(包括休息、低盐饮食、洋地黄和利尿剂等)无效的,称为难治性(顽固性)心力衰竭(以下简称“心衰”)。慢性心力衰竭的病理生理一般来说,慢性充血性心力衰竭是心肌收缩力受到严重的原发性抑制或心室血液动力学极度负荷过重加上收缩力继发性减低的结果。当原发性或继发性收缩力显著减损时,即发生心功能失代偿。心功能是由调节心搏 Some patients with chronic congestive heart failure symptoms persist, known as refractory (refractory) heart failure (hereinafter referred to as “heart failure”), which is ineffective with conventional therapies including rest, low-salt diet, digitalis and diuretics. Pathophysiology of Chronic Heart Failure In general, chronic congestive heart failure is a result of severe primary contractions of cardiac contractility or extreme overload of ventricular hemodynamics coupled with a secondary reduction in contractility. When the primary or secondary contractility significantly impaired, the occurrence of cardiac decompensation. Heart function is adjusted by heartbeat