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目的 :探讨萌动激活赤灵芝孢子粉对小鼠脾细胞IL 2分泌和脾淋巴细胞转化增殖的影响。方法 :实验小鼠随机分成实验组 (低剂量组 4 g/kg/d :高剂量组 :8g/kg/d)和对照组 (与实验组用同体积的生理盐水 ) ,连续用药 1 0天。用3H—TdR掺入法进行检测。结果 :与对照组相比萌动激活赤灵芝孢子粉对小鼠脾细胞IL 2分泌有明显促进作用并能明显提高小鼠脾淋巴细胞转化增殖 ,并有一定的量效关系。结论 :萌动激活赤灵芝孢子粉对小鼠免疫功能有明显的促进作用 ,这可能与其促进细胞因子的分泌和淋巴细胞转化增殖有关。
Objective : To investigate the effects of germination and activation of Ganoderma spore powder on the secretion of IL-2 and the proliferation and proliferation of splenic lymphocytes. Methods: The experimental mice were randomly divided into experimental group (low dose group 4 g/kg/d: high dose group: 8g/kg/d) and control group (same volume of normal saline as experimental group) for continuous medication for 10 days. . 3H-TdR incorporation was used for detection. RESULTS: Compared with the control group, germination activated Ganoderma lucidum spore powder promoted the secretion of IL 2 in mouse spleen cells and significantly increased the spleen lymphocyte transformation and proliferation in mice, and had a certain dose-effect relationship. Conclusion : Germination activates Ganoderma spores powder can significantly promote the immune function of mice, which may be related to its promotion of cytokine secretion and lymphocyte transformation and proliferation.