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目的:探讨影响早产儿贫血发病的相关因素。方法:我院新生儿病房于2007年3月～2010年3月收治早产儿347例,选取发生早产儿贫血154例,按不同胎龄、出生体重、住院后2周内总抽血量进行分组,分别比较贫血出现时间和住院期间血红蛋白(Hb)最低值。结果:胎龄≤34周、出生体重≤1500g的早产儿,贫血出现的平均时间分别为12.8天,13.4天,Hb平均最低值分别为88.7g/L,90.2g/L,随着胎龄和出生体重的增加,贫血出现的时间越晚,程度越轻(P<0.01);住院期间总抽血量<10mL/Kg,贫血出现时间16.,Hb平均最低值为111.3g/L,较≥10ml/Kg组贫血出现晚,程度轻(P<0.01)。结论:胎龄越小、出生体重越低,贫血出现时间越早、贫血程度越重。医源性失血可加重早产儿贫血。
Objective: To investigate the related factors that affect the incidence of anemia in preterm infants. Methods: The neonatal ward in our hospital was treated 347 cases of premature children from March 2007 to March 2010, 154 cases of anemia in preterm infants were selected, according to different gestational age, birth weight, total blood draw within 2 weeks after hospitalization , Respectively, compared anemia and hospitalization during the lowest value of hemoglobin (Hb). Results: The average time of occurrence of anemia in gestational age≤34weeks and birth weight≤1500g was12.8days and13.4days, respectively. The mean Hb was 88.7g / L, 90.2g / L, respectively. With the increase of gestational age and (P <0.01). The total amount of blood drawn during hospitalization was less than 10 mL / Kg, the time of anemia was 16. The mean minimum value of Hb was 111.3 g / L, which was higher than that of ≥ Anemia in the 10ml / Kg group was late and mild (P <0.01). Conclusion: The smaller the gestational age, the lower the birth weight, the earlier the onset of anemia and the more severe the anemia. Iatrogenic bleeding can aggravate anemia in preterm infants.