肝细胞生长因子 (HGF)是从暴发性肝炎患者血浆和鼠血小板中发现的一种促有丝分裂因子 ,后来发现其在髓系白血病患者骨髓及血浆水平明显高于急淋白血病和正常人 ,而缓解期患者 HGF水平显著下降 ,接近正常人水平。研究表明部分髓系白血病细胞产生 HGF,进而剌激自身生长。l　 HGF Hepatocyte growth factor (HGF) is a mitogenic factor found in plasma and murine platelets of patients with fulminant hepatitis. It was later found to be significantly higher in patients with myeloid leukemia at bone marrow and plasma levels than in acute leukemia and normal controls. The level of HGF in the patients decreased significantly and was close to the normal level. Studies have shown that some myeloid leukemia cells produce HGF, which in turn stimulates their own growth. l HGF