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小剂量顺铂连续静脉滴注加静脉注射丝裂霉素治疗恶性上腔静脉综合征１９例。完全缓解１７例，有效率８９．４％；缓解者中最短存活半年，最长已存活１年来复发。其中８例患者治疗第１天后自觉颜面部肿胀减轻，７～１０天上腔静脉综合征消失，化疗３个疗程后纵隔及肺部肿块明显缩小，腔静脉受压及癌栓消失。此法副作用较轻，未见肾、耳毒性和骨髓抑制不良反应，少数患者可引起肌酐、尿素氮升高、一般停药后可自愈。
Small doses of cisplatin continuous intravenous infusion plus intravenous mitomycin in the treatment of malignant superior vena cava syndrome in 19 cases. Complete remission in 17 cases, the effective rate of 89.4%; remission in the shortest survival of six months, the longest survived 1 year recurrence. In 8 of them, the sensation of sensory facial swelling was relieved on the first day after treatment, and the superior vena cava syndrome disappeared on the 7th to 10th days. After 3 courses of chemotherapy, the mediastinal and pulmonary masses were significantly reduced, and the vena cava pressure and tumor plug disappeared. This method has less side effects, no kidney, ototoxicity and bone marrow suppression adverse reactions, a small number of patients can cause creatinine, elevated urea nitrogen, the general withdrawal may be self-healing.