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目的了解天津市医院抗菌药物输液处方合理性。方法选取天津市11所二、三级医疗机构,随机抽取每所医院的处方,记录输液用抗菌药物处方的患者及处方的基本情况,采用回顾性多中心的调查方法 ,利用SPSS软件对抗菌药物输液处方的配伍情况、用法用量、给药途径等方面数据进行统计和分析。结果二、三级医疗机构抗菌药物使用率的差异有统计学意义(χ2=45.67,P<0.01),二级医疗机构比三级医疗机构输液用抗菌药物使用率高;不含抗菌药物处方与含抗菌药物处方相比,在配伍、给药间隔、用法用量方面的差异有统计学意义(χ2=45.80,P<0.01;χ2=550.4,P<0.01;χ2=102.52,P<0.01),不含抗菌药物处方更为合理。结论抗菌药物输液处方基本合理,但还存在不合理之处,有待进一步改进。
Objective To understand the rational prescription of antimicrobial infusion in Tianjin hospital. Methods A total of 11 secondary and tertiary medical institutions in Tianjin were selected and the prescriptions of each hospital were randomly selected. The basic information of patients who prescribed antimicrobial drugs for infusion and the prescriptions were recorded. A retrospective, multicenter survey was conducted to evaluate the efficacy of antibacterials Infusion prescription compatibility, usage and dosage, route of administration and other aspects of data statistics and analysis. Results The rates of antibacterials utilization in the second and third level medical institutions were statistically significant (χ2 = 45.67, P <0.01). The occupational rates of antibacterials in the secondary medical institutions were higher than those in the third grade medical institutions. Compared with prescriptions containing antibiotics, there was significant difference in compatibility, administration interval and usage dosage (χ2 = 45.80, P <0.01; χ2 = 550.4, P <0.01; χ2 = 102.52, P <0.01) Contains antibacterial drugs prescription more reasonable. Conclusion The prescription of antibacterial drug infusion is basically reasonable, but there are still unreasonable points to be further improved.