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目的探讨养心氏片联合胺碘酮治疗冠心病室性早搏的疗效及对缺血症状的改善情况。方法将66例冠心病室性早搏患者随机分为3组,联合治疗组(24例)口服养心氏片及胺碘酮片;胺碘酮组(20例)口服胺碘酮片;养心氏片组(22例)口服养心氏片,3组疗程均为4周。结果改善临床症状方面,联合治疗组总有效率为91.67%,胺碘酮组为80.00%,养心氏片组为68.18%。联合治疗组与口服养心氏组、胺碘酮组比较有统计学意义。心律失常疗效联合治疗组总有效率为95.83%,胺碘酮组为80.00%,养心氏片组为72.73%。3组比较有统计学意义(P<0.05)。结论养心氏片和胺碘酮联用对治疗冠心病室性早搏疗效确切、安全,并可改善患者心肌缺血的临床症状。
Objective To investigate the curative effect of Yangxin tablets combined with amiodarone on ventricular premature beats of coronary heart disease and the improvement of ischemic symptoms. Methods 66 patients with premature ventricular contractions of coronary heart disease were randomly divided into 3 groups, the combination therapy group (24 cases) oral Yangxin tablets and amiodarone tablets; amiodarone group (20 cases) oral amiodarone tablets; Tablet group (22 cases) oral Yang Xin tablets, 3 treatment groups were 4 weeks. Results In improving clinical symptoms, the total effective rate was 91.67% in the combined treatment group, 80.00% in the amiodarone group and 68.18% in the Yangxin tablets group. Combination therapy group and oral Yang Xin’s group, amiodarone group was statistically significant. The total effective rate of arrhythmia combined therapy group was 95.83%, amiodarone group was 80.00%, Yang Xin tablets group was 72.73%. The three groups were statistically significant (P <0.05). Conclusion Yang Xin tablets and amiodarone combined treatment of coronary heart disease premature ventricular contractions curative effect is safe, and can improve the clinical symptoms of myocardial ischemia.