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目的 了解ICU患者建立人工气道后获得性肺部感染的病原菌及药敏情况 ,探讨ICU获得性肺部感染的危险因素及抗菌药物的合理应用。方法 对 2 9例建立人工气道后获得性肺部感染的ICU患者的痰增减及药敏结果进行分析。结果 5 1次痰标本共培养出 6 9株细菌和 12株真菌 ,其中革兰氏阴性菌 46株(72 4 6 %) ,尤以铜绿假单胞菌居多 (2 2株 ,2 7 16 %)。结果 本组ICU患者建立人工气道后获得性肺部感染的病原菌以革兰氏阴性菌为主 ,五种主要致病菌对各种抗生素均有不同程度的耐药。针对造成感染的各种因素应制定一系列的防范措施 ,同时对危重患者的抗菌治疗应有效、合理地用药 ,尽早分离病原菌 ,一旦病原菌确定 ,应予以针对性药物治疗。
Objective To understand the pathogens and drug susceptibility of patients with ICU acquired pulmonary infection after artificial airway, to explore the risk factors of ICU acquired pulmonary infection and rational use of antimicrobial agents. Methods The sputum changes and drug susceptibility results of 29 ICU patients with acquired pulmonary infection after establishment of artificial airway were analyzed. Results A total of 6 9 strains of bacteria and 12 strains of fungi were cultured in 51 sputum specimens, of which 46 strains (72.4%) were Gram-negative bacteria, especially Pseudomonas aeruginosa (22 strains, 276% ). Results The pathogenic bacteria of acquired pulmonary infection in artificial ICU patients were mainly Gram-negative bacteria. The five major pathogens had different degrees of resistance to various antibiotics. For a variety of factors that cause infection should develop a series of preventive measures, while the antimicrobial treatment of critically ill patients should be effective and rational use of drugs, as soon as possible to isolate pathogens, once the pathogen identification, should be targeted drug treatment.