胺碘酮是一种兼有机房性与室性心律失常作用的药物。早期认为该药半衰期较长,使其抗心律失常作用迟缓,但大剂量口服有效地缩短延滞时间。本文旨在对胺碘酮静脉加口服与单纯口服方法加以比较,评价每种给药方案控制室性心律失常所需时间及其累积剂量。方法:20例连续病人均有慢性室性心律失常史,常规药物治疗不能耐受或无效者,部分病例应用茚满丙二胺、室安卡因、劳卡胺、慢心律治疗无效者。家族性 Q-T 延长综合征及Ⅰ度以上房室阻滞除外。 Amiodarone is a combination of both room and ventricular arrhythmia drugs. Early that the drug has a longer half-life, making it anti-arrhythmic slow, but high-dose oral shorten the effective delay. This paper aims to compare the oral and the simple oral route of amiodarone intravenously to evaluate the time required for each dosing regimen to control ventricular arrhythmias and its cumulative dose. Methods: All 20 consecutive patients had a history of chronic ventricular arrhythmias. Patients were unable to tolerate or ineffective with conventional drug therapy. In some cases, indanepropanediamine, ventricular card anecane, rancarine and ineffective bradyarrhythmias were used. Familial Q-T extended syndrome and more than a degree except for atrioventricular block.