含有Tc≡N多重键的~(99m)Tc-放射性药物制备方法由Baldas及其同事最先提出,其中包括在浓的HX(X=Cl、Br)存在下〔~(99m)TcO_4〕-与NaN_3的反应.这条使反应向着生成〔~(99m)TcNX_4〕-化合物的路线有几个不利条件,特别是最终产物产额不高,并且整个过程不能实现无菌和无热原条件.作者开发了一个新方法,该法在最终化合物中 The preparation of ~ (99m) Tc-radiopharmaceuticals containing a Tc≡N multiple bond was first proposed by Baldas and coworkers, including [~ (99m) TcO_4] - in the presence of concentrated HX (X = Cl, Br) NaN 3 This reaction led to several adverse reactions towards the formation of [~ (99m) TcNX_4] - compounds, especially the low yield of the final product and the fact that the whole process could not achieve the conditions of aseptic and pyrogen-free. A new method was developed that is in the final compound