论文部分内容阅读
视网膜母细胞瘤是婴幼儿眼病中最严重、危害性最大的一种恶性肿瘤,具有家族遗传倾向。目前,对于此肿瘤的发生和发展尚无有效的预防措施。近年来,有人注意到视网膜母细胞瘤病毒病因学的研究,Mukai报导,将人体DNA病毒注射入鼠眼内,于注射后73～167天内,有44.4％的注射眼发生了视网膜肿瘤,并在下一代新生年令三天的鼠眼中发现恶性细胞,这种变异细胞对病毒特异的萤光素标记抗体有显著的倾向性;而对照动物无视网膜肿瘤发生。此实验说明是否病毒感染在病因学上有意义,尚待研究解
Retinoblastoma is the most serious and most harmful malignant tumor in infants and young children with familial genetic predisposition. At present, there is no effective preventive measures for the occurrence and development of this tumor. In recent years, it has been noted that etiology of retinoblastoma virus research, Mukai reported that the injection of human DNA virus into the mouse eye, within 73 to 167 days after injection, 44.4% of the injected eye retinal tumor, and in The next generation of newborn rats found malignant cells in the murine eye for three days, and the mutant cells showed a significant predisposition to a virus-specific luciferin-labeled antibody; whereas the control animals had no retinal tumor. This experiment shows whether the etiological significance of viral infection remains to be studied